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Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Engineering doi: 10.1016/j.eng.2022.10.010

Abstract: The traditional Chinese medicine formulation Pien Tze Huang (PTH) can suppress inflammatory diseases.

Keywords： Pien Tze Huang     Non-alcoholic steatohepatitis     Gut barrier function     Gut microbiota    

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Plant Traits for Phytoremediation in the Tropics Article

Xiangting Cleo Chen, Liling Huang, Tze Hsien Agnes Chang, Bee Lian Ong, Say Leong Ong, Jiangyong Hu

Engineering 2019, Volume 5, Issue 5,   Pages 841-848 doi: 10.1016/j.eng.2019.07.019

Abstract:

Water is a limited and valuable resource. Singapore has four national sources of water supply, one of which is natural precipitation. Pollutants collected in stormwater runoff are deposited into drainage systems and reservoirs. Major nutrient pollutants found in local stormwater runoff include nitrate and phosphate, which may cause eutrophication. Bioretention systems are efficient in removing these pollutants in the presence of plants. This paper discusses plant traits that can enhance the phytoremediation of nutrient pollutants in stormwater runoff for application in bioretention systems. The plant species studied showed variations in chlorophyll florescence, leaf greenness, biomass production, and nitrate and phosphate removal. In general, dry biomass was moderately correlated to nitrate and phosphate removal (r = 0.339–0.501). Root, leaf, and total dry biomass of the native tree species showed a moderate to strong correlation with nitrate removal (r = 0.811, 0.657, and 0.727, respectively). Leaf dry biomass of fastgrowing plants also showed a moderate to strong relationship with the removal of both pollutants (r = 0.707 and 0.609, respectively). Root dry biomass of slow-growing plants showed a strong relationship with phosphate removal (r = 0.707), but the correlation was weaker for nitrate removal (r = 0.557). These results are valuable for choosing plants for application in bioretention systems.

Keywords： Nitrogen     Phosphorus     Plant traits     Bioretention system     Stormwater     Tropical plant     Nutrient pollutant     Native plants    

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Impact of photosynthesis and transpiration on nitrogen removal in constructed wetlands

LUO Weiguo, WANG Shihe, HUANG Juan, YAN Lu, HUANG Jun

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 3,   Pages 316-319 doi: 10.1007/s11783-007-0053-x

Abstract: To determine the impact of photosynthesis and transpiration on nitrogen removal in wetlands, an artificial wetland planted with reeds was constructed to treat highly concentrated domestic wastewater. Under different meteorological and hydraulic conditions, the daily changes of photosynthesis and transpiration of reeds, as well as nitrogen removal efficiency were measured. It was found that net photosynthesis rate per unit leaf area was maintained on a high level (average 19.0 yDol CO/(m · s) ) from 10:00 to 14:00 in July 2004 and reached a peak of 21.1 μmol CO/(m · s) when Photon Flux Density was high during the day. Meanwhile, TN and NH-N removal efficiency rose to 79.6% and 89.6%, respectively–the maximum values observed in the test. Correlation coefficient analysis demonstrated a positive correlation among photon flux density, net photosynthetic rate, transpiration rate, and TN and NH-N removal efficiency. In contrast, there was a negative correlation between stomatal conductance and TN and NH-N removal efficiency. Results suggest that the photosynthesis and transpiration of wetland plants have a great impact on nitrogen removal efficiency of wetlands, which can be enhanced by an increase in the photosynthesis and transpiration rate. In addition, the efficiency of water usage by reeds and nitrogen removal efficiency could be affected by the water level in wetlands; a higher level boosts nitrogen removal efficiency.

Keywords： transpiration     Correlation coefficient     nitrogen removal     artificial wetland     impact    

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Occurrence of estrogenic endocrine disrupting chemicals concern in sewage plant effluent

Yan SUN, Huang HUANG, Ying SUN, Chao WANG, Xiaolei SHI, Hongying HU, Takashi KAMEYA, Koichi FUJIE

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 1,   Pages 18-26 doi: 10.1007/s11783-013-0573-5

Abstract: The purpose of this study was to give a worldwide overview of the concentrations of typical estrogenic endocrine disrupting chemicals (EDCs) in the effluent of sewage plants and then compare the concentration distribution of the estrogenic EDCs in ten countries based on the survey data of the estrogenic EDCs research. The concentrations of three main categories (totally eight kinds) of estrogenic EDCs including steroidal estrogens (estrone (E1), estradiol (E2), estriol (E3) and 17α-ethynylestradiol (EE2)), phenolic compounds (nonylphenol (NP) and bisphenol A (BPA)) and phthalate esters (dibutyl phthalate (DBP) and dibutyl phthalate (2-ethylhexyl) phthalate (DEHP)) in the effluents of sewage plants reported in major international journals over the past decade were collected. The statistics showed that the concentration distributions of eight kinds of EDCs were in the range of ng·L to μg·L . The concentrations of steroidal estrogens mainly ranged within 50.00 ng·L , and the median concentrations of E1, E2, E3 and EE2 were 11.00, 3.68, 4.90 and 1.00 ng·L , respectively. Phenolic compounds and phthalate esters were found at μg·L level (some individual values were at the high level of 40.00 μg·L ). The median concentrations of BPA, NP, DBP and DEHP were 0.06, 0.55, 0.07 and 0.88 μg·L , respectively. The concentrations of phenolic compounds and phthalate esters in the effluents were higher than that of steroids estrogens. The analysis of the concentration in various ten countries showed that steroids estrogens, phenolic compounds and phthalate esters in sewage plant effluents were detected with high concentration in Canada, Spain and China, respectively.

Keywords： estrogenic endocrine disrupting chemicals     concentration distribution     sewage plant    

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Laser ablation of block copolymers with hydrogen-bonded azobenzene derivatives

Jintang Huang, Youju Huang, Si Wu

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 3,   Pages 450-456 doi: 10.1007/s11705-018-1735-6

Abstract:

Supramolecular assemblies (PS-b-P4VP(AzoR)) are fabricated by hydrogen-bonding azobenzene derivatives (AzoR) to poly(4-vinyl pyridine) blocks of polystyrene-block-poly(4-vinyl pyridine) (PS-b-P4VP). PS-b-P4VP(AzoR) forms phase separated nanostructures with a period of ~75–105 nm. A second length scale structure with a period of 2 µm is fabricated on phase separated PS-b-P4VP(AzoR) by laser interference ablation. Both the concentration and the substituent of AzoR in PS-b-P4VP(AzoR) affect the laser ablation process. The laser ablation threshold of PS-b-P4VP(AzoR) decreases as the concentration of AzoR increases. In PS-b-P4VP(AzoR) with different substituents (R= CN, H, and CH3), ablation thresholds follow the trend: PS-b-P4VP(AzoCN)<PS-b-P4VP(AzoCH3)<PS-b-P4VP(AzoH). This result indicates that the electron donor group (CH3) and the electron acceptor group (CN) can lower the ablation threshold of PS-b-P4VP(AzoR).

Keywords： laser ablation     block copolymers     hydrogen-bond     azobenzene derivatives     supramolecular assembly    

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Approach for natural gas to be a primary energy source in China

Weihe HUANG, Jindian CHEN, Chuan FU, Yan HUANG

Frontiers of Engineering Management 2019, Volume 6, Issue 4,   Pages 467-476 doi: 10.1007/s42524-019-0068-6

Abstract: This work reveals the positioning of natural gas in the evolution of world energy and the general law of its development. In the long-term adjustment of energy structure, natural gas has gradually become the primary energy source because of five factors: policy, resources, technology, facilities, and market. To expedite the revolution of energy production and consumption, China must urgently expand the use of natural gas toward a more positive role in complementing coal and renewable energy and prioritize its usage in three areas, namely, urban gas, power generation, and industrial fuel. Natural gas is expected to account for approximately 15% of China’s total energy consumption in the future. For natural gas to be the primary energy, the exploitation of gas resources must be expanded, resource access must be improved, a flexible trade system must be set up, infrastructure investment must be increased, and the security system must be enhanced.

Keywords： natural gas     energy revolution     primary energy     utilization areas     approaching means    

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A novel method for reconstruction in laparoscopic pancreaticoduodenectomy: an experience of 13 cases

LU Bangyu, HUANG Yubin, CAI Xiaoyong, HUANG Fei, LU Wenqi, XU Jing, LIU Zujun, YAN Yihe, LI Jianjun,

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 369-372 doi: 10.1007/s11684-007-0071-x

Abstract: Laparoscopic pancreaticoduodenectomy (LPD) is a challenging operation to general surgeon. Up to date, only about 135 cases have been reported, 16 cases in China, 119 cases outside China. The reconstruction of alimentary system is a key procedure to ensure success of the whole surgery. It is worth investigating the methods of reconstruction in LPD. A retrospective study is made to investigate the methods of reconstruction in LPD. We analyze 13 cases of LPD performed in our center. Child s or modified Child s method was used to make the reconstruction in our practice. We tried three methods to make the anastomosis of pancreaticojejunostomy, including end-to-end dunking binding pancreaticojejunostomy in two cases, end-to-end dunking pancreaticojejunostomy using interrupted suture in two cases, and duct-to-jejunal end-to-side embedding pancreaticojejunostomy in nine cases. The clinical data was collected and analyzed. Three of four patients, who underwent end-to-end pancreaticojejunostomy, had a little pancreatic leakage, especially in the first case. None of other nine patients, who underwent duct-to-jejunal end-to-side embedding pancreaticojejunostomy, was detected to have pancreatic leakage, and the operating time of these nine cases was less than other four cases. Duct-to-jejunal end-to-side embedding pancreaticojejunostomy is a safe and efficient method of reconstruction in LPD.

Keywords： alimentary     dunking pancreaticojejunostomy     challenging operation     anastomosis     success    

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Pre-chamber turbulent jet ignition of methane/air mixtures with multiple orifices in a large bore constant volume chamber: effect of air-fuel equivalence ratio and pre-mixed pressure

Xiang LI, Wenzheng ZHANG, Zhong HUANG, Dehao JU, Li HUANG, Mingzhi FENG, Xingcai LU, Zhen HUANG

Frontiers in Energy 2019, Volume 13, Issue 3,   Pages 483-493 doi: 10.1007/s11708-019-0631-1

Abstract: Liquefied natural gas (LNG), mainly composed of methane, is in progress to substitute diesel fuel in heavy-duty marine engine for practical, economic, and environmental considerations. However, natural gas is relatively difficult to be ignited in a large bore combustion chamber. A combustion enhancement technique called pre-chamber turbulent jet ignition (TJI) can permit combustion and flame propagation in a large-bore volume. To investigate the effect of air-fuel equivalence ratio and pre-mixed pressure on pre-chamber TJI of methane/air mixtures with multiple orifices in a large bore volume, experimental tests and computational simulations were implemented to study the discharge of hot turbulent jets from six orifices of the pre-chamber. Different initial pressures and air-fuel equivalence ratios were considered to analyze the characteristics of TJI. The asymmetry of the turbulent jet actuated from six different orifices were found due to the asymmetric orientation of the spark plug, resulting in the inhomogeneous distribution of combustion in the constant volume chamber, which should be considered seriously in the marine engine design. Besides, as the premixed pressure increases, it has more effect on the flame propagation and plays a more important role, as it further increases.

Keywords： marine engine     natural gas     methane     turbulent jet ignition (TJI)     pre-chamber    

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Applications of advanced controlmethods in spacecrafts: progress, challenges, and future prospects Review

Yong-chun XIE,Huang HUANG,Yong HU,Guo-qi ZHANG

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 9,   Pages 841-861 doi: 10.1631/FITEE.1601063

Abstract: We aim at examining the current status of advanced control methods in spacecrafts from an engineer’s perspective. Instead of reviewing all the fancy theoretical results in advanced control for aerospace vehicles, the focus is on the advanced control methods that have been practically applied to spacecrafts during flight tests, or have been tested in real time on ground facilities and general testbeds/simulators built with actual flight data. The aim is to provide engineers with all the possible control laws that are readily available rather than those that are tested only in the laboratory at the moment. It turns out that despite the blooming developments of modern control theories, most of them have various limitations, which stop them from being practically applied to spacecrafts. There are a limited number of spacecrafts that are controlled by advanced control methods, among which H2/H∞ robust control is the most popular method to deal with flexible structures, adaptive control is commonly used to deal with model/parameter uncertainty, and the linear quadratic regulator (LQR) is the most frequently used method in case of optimal control. It is hoped that this review paper will enlighten aerospace engineers who hold an open mind about advanced control methods, as well as scholars who are enthusiastic about engineering-oriented problems.

Keywords： Spacecraft control     Robust control     Adaptive control     Optimal control    

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Special issue: City and infrastructure engineering and management

Weihe HUANG, Chunfang LU, Dongping FANG

Frontiers of Engineering Management 2021, Volume 8, Issue 1,   Pages 1-4 doi: 10.1007/s42524-020-0150-0

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Search-and-replace editing of genetic information

Yao LIU, Xingxu HUANG, Xiaolong WANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 231-232 doi: 10.15302/J-FASE-2020322

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Enhanced production of

Shen Huang,Xudong Feng,Chun Li

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 4,   Pages 501-510 doi: 10.1007/s11705-015-1544-0

Abstract: -Glucuronidase from Li-3 (PGUS) can efficiently hydrolyze glycyrrhizin into the more valuable glycyrrhetic acid monoglucuronide. However, a low productivity of PGUS and the lack of an effective separation strategy have significantly limited its industrial applications. Therefore, the production of PGUS has been improved by optimizing both the fermentation and purification strategies. A two-stage fermentation strategy was developed where PGUS was first grown with glucose and then PGUS was produced in the presence of glycyrrhizin as an inducer. By using this strategy, the biomass was increased 1.5 times and the PGUS activity increased 5.4 times compared to that when glycyrrhizin was used as the sole carbon source. The amount of PGUS produced was increased another 16.6% when the fermentation was expanded to a 15-L fermenter. An effective protocol was also established to purify the PGUS using a sequential combination of hydrophobic, strong anion-exchange and gel filtration chromatography. This protocol had a recovery yield of 6% and gave PGUS that was 39 times purer than the crude PGUS. The purified PGUS had a specific activity of 350 U·mg .

Keywords： β-glucuronidase     glycyrrhetic acid monoglucuronide     cell disruption     purification     chromatography    

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Electrochemical performance of thermally-grown SiO

HUANG, X. F. GAN, Q. A. HUANG, J. Z. YANG

Frontiers in Energy 2018, Volume 12, Issue 2,   Pages 225-232 doi: 10.1007/s11708-018-0556-0

Abstract: Direct integration of lithium-ion battery (LIB) with electronic devices on the same Si substrate can significantly miniaturize autonomous micro systems. For achieving direct integration, a barrier layer is essential to be inserted between LIB and the substrate for blocking Li diffusion. In this paper, the feasibility of thermal SiO film as the barrier layer is investigated by electrochemical characterization and X-ray photoelectron spectroscopy (XPS). Due to the negligible side reactions of thermal SiO with electrolyte, the solid electrolyte interphase (SEI) layer formed on the surface of the barrier layer is thin and the SEI content mainly consists of hydrocarbon together with slight polyethylene oxide (PEO), Li PO F , and Li CO . Although 8-nm thermal SiO effectively prevents the substrate from alloying with Li , the whole film changes to Li silicate after electrochemical cycling due to the irreversible chemical reactions of SiO with electrolyte. This degrades the performance of the barrier layer against the electrolyte penetration, thus leading to the existence of Li (in the form of F-Si-Li) and solvent decompositions (with the products of hydrocarbon and PEO) near the barrier layer/substrate interface. Moreover, it is found that the reaction kinetics of thermal SiO with electrolyte decrease significantly with increasing the SiO thickness and no reactions are found in the bulk of the 30-nm SiO film. Therefore, thermal SiO with an appropriate thickness is a promising barrier layer for direct integration.

Keywords： autonomous micro system     direct integration     barrier layer     thermal SiO2 film     X-ray photoelectron spectroscopy (XPS)    

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Title Author Date Type Operation

Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Journal Article

Plant Traits for Phytoremediation in the Tropics

Xiangting Cleo Chen, Liling Huang, Tze Hsien Agnes Chang, Bee Lian Ong, Say Leong Ong, Jiangyong Hu

Journal Article

Han Huang: Deformation and Removal of Semiconductor and Laser Crystals at Extremely Small Scales（2019.10.10

23 Apr 2021

Conference Videos

Impact of photosynthesis and transpiration on nitrogen removal in constructed wetlands

LUO Weiguo, WANG Shihe, HUANG Juan, YAN Lu, HUANG Jun

Journal Article

Occurrence of estrogenic endocrine disrupting chemicals concern in sewage plant effluent

Yan SUN, Huang HUANG, Ying SUN, Chao WANG, Xiaolei SHI, Hongying HU, Takashi KAMEYA, Koichi FUJIE

Journal Article

Laser ablation of block copolymers with hydrogen-bonded azobenzene derivatives

Jintang Huang, Youju Huang, Si Wu

Journal Article

Approach for natural gas to be a primary energy source in China

Weihe HUANG, Jindian CHEN, Chuan FU, Yan HUANG

Journal Article

A novel method for reconstruction in laparoscopic pancreaticoduodenectomy: an experience of 13 cases

LU Bangyu, HUANG Yubin, CAI Xiaoyong, HUANG Fei, LU Wenqi, XU Jing, LIU Zujun, YAN Yihe, LI Jianjun,

Journal Article

Huang Tiejun: Brain like Intelligence (2019-12-10)

10 Dec 2022

Conference Videos

Pre-chamber turbulent jet ignition of methane/air mixtures with multiple orifices in a large bore constant volume chamber: effect of air-fuel equivalence ratio and pre-mixed pressure

Xiang LI, Wenzheng ZHANG, Zhong HUANG, Dehao JU, Li HUANG, Mingzhi FENG, Xingcai LU, Zhen HUANG

Journal Article

Applications of advanced controlmethods in spacecrafts: progress, challenges, and future prospects

Yong-chun XIE,Huang HUANG,Yong HU,Guo-qi ZHANG

Journal Article

Special issue: City and infrastructure engineering and management

Weihe HUANG, Chunfang LU, Dongping FANG

Journal Article

Search-and-replace editing of genetic information

Yao LIU, Xingxu HUANG, Xiaolong WANG

Journal Article

Enhanced production of

Shen Huang,Xudong Feng,Chun Li

Journal Article

Electrochemical performance of thermally-grown SiO

HUANG, X. F. GAN, Q. A. HUANG, J. Z. YANG

Journal Article